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Hepatic Encephalopathy and Nutrition Influences: A Narrative Review
Hepatic encephalopathy (HE) is a potentially reversible neurocognitive condition seen in patients with advanced liver disease. The overt...

Dr. Robert Rahimi
Jan 31 min read
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Lactulose vs polyethylene glycol 3350--electrolyte solution for treatment of overt hepatic encephalopathy: the HELP randomized clinical trial
Importance: Hepatic encephalopathy (HE) is a common cause of hospitalization in patients with cirrhosis. Pharmacologic treatment for...

Dr. Robert Rahimi
Jan 32 min read
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End-stage liver disease complications
Purpose of review: Chronic liver disease causes significant morbidity and mortality because of any number of complications including...

Dr. Robert Rahimi
Jan 31 min read
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Novel Ammonia-Lowering Agents for Hepatic Encephalopathy
Hepatic encephalopathy (HE) is a common complication of cirrhosis, leading to frequent hospitalizations. Because ammonia is thought to play

Dr. Robert Rahimi
Jan 31 min read
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Hepatic Encephalopathy: Pharmacological Therapies Targeting Ammonia
Hepatic encephalopathy (HE) is a major complication in patients with decompensated cirrhosis, leading to higher readmission rates causing a

Dr. Robert Rahimi
Jan 31 min read
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TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial
Increased de novo lipogenesis creates excess intrahepatic fat and lipotoxins, propagating liver damage in nonalcoholic steatohepatitis. TVB-

Dr. Robert Rahimi
Jan 32 min read
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The Current Hepatic Encephalopathy Pipeline
Hepatic encephalopathy (HE) is a complication of acute or chronic liver failure; its mechanism is complex, involving multiple organ...

Dr. Robert Rahimi
Jan 31 min read
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The novel SALT-M score predicts 1-year post-transplant mortality in patients with severe acute-on-chronic liver failure
Background & aims: Twenty-eight-day mortality ranges from 30-90% in patients with acute-on-chronic liver failure grades 2/3 (severe...

Dr. Robert Rahimi
Jan 32 min read
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Complications of cirrhosis
Purpose of review: Chronic liver disease (CLD) causes significant morbidity and mortality, mainly due to complications [hepatic...

Dr. Robert Rahimi
Jan 31 min read
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Serum Ammonia Levels Do Not Correlate With Overt Hepatic Encephalopathy Severity in Hospitalized Patients With Cirrhosis
Although ammonia is involved in the pathophysiology of hepatic encephalopathy (HE), the use of ammonia levels in clinical practice is...

Dr. Robert Rahimi
Jan 31 min read
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Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management of psoriasis with systemic nonbiologic therapies
Psoriasis is a chronic inflammatory disease involving multiple organ systems and affecting approximately 2% of the world's population. In...

Dr. Robert Rahimi
Jan 31 min read
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Hepatic Encephalopathy: Current and Emerging Treatment Modalities
Hepatic encephalopathy (HE) is a potentially reversible neurocognitive complication of cirrhosis. It has been reported in at least 30% of...

Dr. Robert Rahimi
Dec 17, 20241 min read
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